A historic case study on chronic Lyme disease

0.5 CME. This presentation provides physicians with clinically useful information that will help them assist patients with manifestations of Chronic Lyme disease.


Kenneth B. Liegner, MD


This presentation provides physicians with clinically useful information that will help them assist patients with manifestations of Chronic Lyme disease.

Learning objectives

  1. List some of the complexities regarding the diagnosis and treatment of Lyme disease.
  2. Recognize that Lyme disease can be ‘serovariable’ (results in some individuals can be seronegative, borderline or positive despite active Lyme infection).
  3. State that Chronic Lyme disease is a bona fide entity.
  4. Recall that Borrelia burgdorferi can exist within biofilm in patients.
  5. Recognize that long-term antimicrobial treatment is necessary for some individuals, however, current methods may fail to eradicate the infection.
  6. Recognize that improved methods of treatment for Lyme disease in all of its stages are urgently needed and should be a very high priority for the international biomedical research community.

This session, A historic case study on chronic Lyme disease, is approved for 0.5 enduring AAFP Prescribed credits.

AAFP Prescribed credit is accepted by the American Medical Association as equivalent to AMA PRA Category 1 credit(s)™ toward the AMA Physician’s Recognition Award. When applying for the AMA PRA, Prescribed credit earned must be reported as Prescribed, not as Category 1.

The AAFP has reviewed One Health Medical Education for a Changing Climate and deemed it acceptable for AAFP credit. Term of approval is from 01/02/2024 to 01/01/2025. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


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Shor, S.; Green, C.; Szantyr, B.; Phillips, S.; Liegner, K.; Burrascano, J.J., Jr.; Bransfield, R.; Maloney, E.L. Chronic Lyme Disease: An Evidence-Based Definition by the ILADS Working Group. Antibiotics 2019, 8, 269.

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Clinical Courier. Vol 9, No 5. August 1991. NIH State-of-the-Art Conference. NIAID/NIAMSD. ISSN 0264-6684.Diagnosis and Treatment of Lyme DiseaseLiegner, KB In the Crucible of Chronic Lyme Disease. Xlibris. 2015. www.inthecrucibleofchroniclymedisease.com

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Course Includes

  • 1 Lesson
  • 2 Quizzes
  • Course Certificate