Call for international data sharing from the clinical trenches in Ireland

CME Pending. This module provides an overview of the tick borne illness epidemic in the UK and Ireland and the need for international data sharing and collaboration in the field of vector borne illness.

John Lambert, MD
Full Professor of Medicine and Infectious Diseases, Mater Hospital and UCD, Dublin 

Description

This module provides an overview of the tick borne illness epidemic in the UK and Ireland and the need for international data sharing and collaboration in the field of vector borne illness.

Learning objectives

  1. Discuss the vast array of tick borne pathogens
  2. Describe the serious issue of prevalence of infected ticks in the UK and Ireland
  3. Discuss why better surveillance, data sharing and collaboration under the One Health model would be useful for the field at large.

Application for CME credit has been filed with the American Academy of Family Physicians. Determination of credit is pending.

Reference List:

NICE Lyme disease: Diagnosis and management [M] person to person transmission; 2018; ISBN 9781473129191.

Lakos, A.; Solymosi, N. Maternal Lyme borreliosis and pregnancy outcome. Int. J. Infect. Dis. 2010, 14, e494-8.

MacDonald, A.B. Human fetal borreliosis, toxemia of pregnancy, and fetal death. Zentralbl. Bakteriol. Mikrobiol. Hyg. A. 1986, 263, 189–200.

MacDonald, A.B. Gestational Lyme Borreliosis. Rheum. Dis. Clin. North Am. 1989, 15, 657–677.

Maraspin, V.; Cimperman, J.; Lotrič-Furlan, S.; Pleterski-Rigler, D.; Strle, F. Treatment of erythema migrans in pregnancy. Clin. Infect. Dis. 1996, 22, 788–793.

Maraspin, V.; Cimperman, J.; Lotric Furlan, S.; Pleterski-Rigler, D.; Strle.F Erythema Migrans in Pregnancy. Wein Klin Wochenschr 1999, 10, 22–23.

Maraspin, V.; Ružić-Sabljić, E.; Pleterski-Rigler, D.; Strle, F. Pregnant women with erythema migrans and – -isolation of borreliae from blood: course and outcome after treatment with ceftriaxone. Diagn. Microbiol. Infect. Dis. 2011, 71, 446–8.

Markowitz, L.; Steere, A.; Benach, J.; Slade, J.; Broome CV Lyme Disease During Pregnancy. JAMA 1986, 255, 3394–6.

Nadal, D.; Hunziker, U.A.; Bucher, H.U.; Hitzig, W.H.; Duc, G. Infants born to mothers with antibodies against Borrelia burgdorferi at delivery. Eur. J. Pediatr. 1989, 148, 426–427.

Strobino, B.A.; Williams, C.L.; Abid, S.; Chalson, R.; Spierling, P. Lyme disease and pregnancy outcome: a prospective study of two thousand prenatal patients. Am. J. Obstet. Gynecol. 1993, 169, 367–74.

Strobino, B.; Abid, S.; Gewitz, M. Maternal Lyme disease and congenital heart disease: A case-control study in an endemic area. Am. J. Obstet. Gynecol. 1999, 180, 711–6.

Williams, C.L.; Strobino, B.; Weinstein, A.; Spierling, P.; Medici, F. Maternal Lyme disease and congenital malformations: a cord blood serosurvey in endemic and control areas. Paediatr. Perinat. Epidemiol. 1995, 9, 320–330.

MacDonald, A.B.; Benach, J.L.; Burgdorfer, W. Stillbirth following maternal Lyme disease. N. Y. State J. Med. 1987, 87, 615–6.

Gerber, M.A.; Zalneraitis, E.L. Childhood neurologic disorders and Lyme disease during pregnancy. Pediatr. Neurol. 1994, 11, 41–43.

Lavoie, P.; Duray, P.; et al Culture positive, seronegative, transplacental Lyme borreliosis infant mortality. Arthritis Rheum 1987, 3.

Walsh, C.A.; Mayer, E.W.; Baxi, L. V. Lyme disease in pregnancy: Case report and review of the literature. Obstet. Gynecol. Surv. 2007, 62, 41–50.

Schaumann, R.; Fingerle, V.; Buchholz, K.; Spencker, F.B.; Rodloff, A.C. Facial Palsy Caused by Borrelia Infection in a Twin Pregnancy in an Area of Nonendemicity. Clin. Infect. Dis. 1999, 29, 955–956.

Weber, K.; Bratzke, H.J.; Neubert, U.; Wilske, B.; Duray, P.H. Borrelia burgdorferi in a newborn despite oral penicillin for Lyme borreliosis during pregnancy. Pediatr. Infect. Dis. J. 1988, 7, 286–9.

Moysa C, Murtagh R, Lambert JS. Potential Persistent Borrelia Infection and Response to Antibiotic Therapy; a Clinical Case Study and Review of Recent Literature. Antibiotics (Basel). 2019 Nov 14;8(4):223. doi: 10.3390/antibiotics8040223. PMID: 31739409; PMCID: PMC6963185.

Rogerson AG, Lloyd VK. Lyme Disease Patient Outcomes and Experiences; A Retrospective Cohort Study. Healthcare (Basel). 2020 Sep 4;8(3):322. doi: 10.3390/healthcare8030322. PMID: 32899834; PMCID: PMC7551198.

Lambert JS, Cook MJ, Healy JE, Murtagh R, Avramovic G, Lee SH. Metagenomic 16S rRNA gene sequencing survey of Borrelia species in Irish samples of Ixodes ricinus ticks. PLoS One. 2019 Apr 15;14(4):e0209881. doi: 10.1371/journal.pone.0209881. PMID: 30986208; PMCID: PMC6464168.

About Instructor

Not Enrolled

Course Includes

  • 1 Lesson
  • 2 Quizzes
  • Course Certificate